BioCeuticals MTHF 60c

5-methyltetrahydrofolate (5-MTHF) is the most active metabolite of folic acid, bypassing all of the enzymatic activation steps in the conversion of folic acid to the biologically active 5-MTHF. Directly utilised by the body, 5-MTHF supports healthy methylation, homocysteine metabolism, DNA replication and foetal development.

Features:

• Contains 5-MTHF, the most active form of folic acid.
• Supports healthy brain and nervous system function.
• Supports healthy methylation pathways and homocysteine metabolism.
• Is involved in growth and cellular replication, and supports healthy replication of DNA through healthy DNA methylation.
• Provides 500mcg of 5-MTHF (active folate), which contributes to the normal growth of the foetus.
• If taken daily for one month before conception and during pregnancy, may reduce the risk of women having a child with birth defects of the brain and/or spinal cord such as the neural tube defects known as spina bifida and anencephaly.
• Helps maintain normal blood by helping to form red blood cells and assisting with their function.
  

Ingredients

No added dairy, gluten, shellfish, soy protein, yeast.

Pregnancy friendly.

Vegan and vegetarian friendly.

Cautions

• If symptoms persist, consult your healthcare practitioner.
• Do not exceed the stated dose except on medical advice.
• If you have had a baby with neural tube defect/spina bifida, seek medical advice.
• Vitamin supplements should not replace a balanced diet.
• Always read the label. Use only as directed.

• Supplementation with folic acid and 5-MTHF is recommended during pregnancy at an intake of between 400-600mcg per day.
• Some concern exists that supplementation at high doses of folic acid could mask a B12 deficiency state.
• Supplementation with 5-MTHF appears to side-step this potential problem. Since 5-MTHF can only be converted to 5,10-MTHF after participating in homocysteine recycling with vitamin B12, it may not mask a B12 deficiency because 5-MTHFis not active in DNA synthesis without the help of B12.
• At doses up to 50mg a day, GI complaints, insomnia, irritability and fatigue have been occasional side effects.
• Theoretically, high doses of folic acid might increase toxicity of 5-fluorouracil.
• There is some evidence that folic acid supplements reduce the efficacy of methotrexate in the treatment of acute lymphoblastic leukemia, and theoretically they could reduce its efficacy in the treatment of other cancers.
• Folic acid, folinic acid or 5-MTHF supplementation does not appear to interfere with methotrexate's anti-arthritic or anti-inflammatory activity.
• Folic acid can have direct convulsant activity in some people, reversing the effects of phenobarbital and primidone, and worsening seizure control.
  

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